
Creatine Monohydrate

Who should not take creatine?
Athletes and fitness enthusiasts involved in activities that require short - burst power, such as sprinters, weightlifters, and basketball players, can benefit significantly. It can also be useful for those looking to increase muscle mass, as it may enhance muscle recovery and protein synthesis. Even some non - athletes who want to improve their physical performance during high - intensity workouts can consider it.

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Product name: |
Creatine Monohydrate |
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Synonyms: |
N-GUANYL-N-METHYLGLYCINE;N-GUANYL-N-METHYLGLYCINE MONOHYDRATE;N-METHYL-N-GUANYLGLYCINE MONOHYDRATE;N-AMIDINOSARCOSINE;
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Formula: |
C4H9N3O2 H2O |
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Molecular weight: |
418.30 |
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CAS number: |
6020-87-7 |
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Appearance |
White crystalline powder |
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Assay: |
> 99.50% |
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Mesh: |
80 mesh; 200 mesh or customized |
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Residual on ignition: |
NMT 0.10% |
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Creatinine: |
NMT 100.00 ppm |
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Dicyandiamide: |
NMT 50.00 ppm |
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Dihydrotriazine: |
NMT 0.0005% |
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MOQ: |
25kg |
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Certification: |
ISO9001, FSSC22000, Organic |
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Package: |
25kg/Carton or customized |
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Shelf Life: |
24 Months under room temperature |
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Application |
Food supplement, food additive, feed additive |
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Storage: |
Store in a well-closed container away from moisture and direct sunlight. |
Mechanism of Action
The primary role of creatine monohydrate is to serve as a rapidly available energy source for cells, particularly in skeletal muscle and the brain.
ATP Regeneration: After ingestion, creatine is phosphorylated to form phosphocreatine (PCr). During short bursts of high-intensity exercise, phosphocreatine donates a phosphate group to adenosine diphosphate (ADP) via the enzyme creatine kinase, rapidly regenerating adenosine triphosphate (ATP)-the body's primary energy currency . This process helps sustain muscle contraction and delays fatigue.
Cellular Bioenergetics: By replenishing ATP levels, creatine supports cellular energy homeostasis. It also plays a role in stabilizing biological membranes and may stimulate protein synthesis or reduce protein degradation.

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Product characteristics |
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Product name |
Creatine Monohydrate |
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Synonyms: |
N-GUANYL-N-METHYLGLYCINE;N-GUANYL-N-METHYLGLYCINE, MONOHYDRATE;N-METHYL-N-GUANYLGLYCINE MONOHYDRATE;N-AMIDINOSARCOSINE; |
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Formula: |
C4H9N3O2 H2O |
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Molecular: |
149.15 |
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Structure: |
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CAS #: |
64452-96-6 |
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Product profile |
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Color: |
White crystalline powder |
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Identification: |
The retention time of the major peak of the sample solution corresponds to That of the standard solution, as obtained in the assay. |
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Loss on drying: |
10.50~12.00% |
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Residual on ignition: |
NMT 0.10% |
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Sulfate: |
NMT 0.10% |
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Iron: |
NMT 10.00 ppm |
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Heavy metals: |
NMT 10.00 ppm |
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Lead: |
NMT 1.00 ppm |
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Arsenic: |
NMT 1.00 ppm |
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Cadmium: |
NMT 1.00 ppm |
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Mercury: |
NMT 0.10 ppm |
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Creatinine: |
NMT 100.00 ppm |
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Dicyandiamide: |
NMT 50.00 ppm |
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Dihydrotriazine: |
NMT 0.0005% |
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Any unspecfied impurity: |
NMT 0.10% |
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Total unspecified impurity: |
NMT 1.50% |
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Total impurities |
NMT 2.00% |
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Assay: |
99.50~102.00%(on basis) |
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Particle size: |
NLT 70% through 200 mesh |
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Bulk density: |
NLT 430g/L |
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Tapped density: |
NLT 550g/L |
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Total bacterial count: |
NMT 100 cfu/g |
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Mold&yeast: |
NMT 100 cfu/g |
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E.Coli: |
Negative/g |
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Salmonella: |
Negative/10g |
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Staphylococcus aureus: |
Negative/g |
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Packaging |
25kg/Carton |
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Storage |
Keep product in a cool&dry place and avoid sunlight exposure |
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Shelf life |
24 month with packing unopened |

Sports Nutrition & Nutraceuticals: This is the largest application area. Creatine monohydrate is a cornerstone ingredient in pre-workout formulas, post-workout recovery blends, and standalone supplements for athletes and fitness enthusiasts aiming to increase power output, muscle mass, and training capacity .
Food & Beverage Industry: Creatine monohydrate is used as a functional ingredient for fortifying foods and beverages. Common applications include enhanced water beverages, protein bars, and other functional foods aimed at active consumers . Its GRAS status supports this use.

1. Boosts High - Intensity Performance
Creatine monohydrate powers up the body's energy system. It quickly turns ADP back into ATP, the energy currency of cells. This means more immediate energy for short, intense activities like sprinting or weightlifting. As a result, athletes can put out more power, lifting heavier or running faster.
2. Aids Muscle Growth and Recovery
It helps muscle cells hold more water, which triggers protein synthesis. This leads to muscle growth. After a tough workout, creatine monohydrate reduces fatigue and speeds up glycogen replenishment. So, muscles recover faster, allowing for more frequent and intense training.
3. Well - Researched and Trusted
There's a lot of scientific research on creatine monohydrate. Studies have shown its effectiveness in improving performance and muscle mass. It has a long - standing good reputation in the sports and fitness world. Coaches and athletes widely recommend it.
4. High - Quality and Convenient
Good - quality creatine monohydrate is pure, free from bad stuff. Its stable structure means it keeps well. Usually sold as a powder, it's easy to mix with drinks. You can take it before or after a workout as part of your daily routine.

Q1: What is Creatine Monohydrate?
A1: Creatine monohydrate is a natural compound found in the body, mainly in muscles. It consists of creatine bound to a single molecule of water. It plays a crucial role in energy production during high - intensity, short - duration exercises by helping to regenerate ATP (adenosine triphosphate), the body's main energy - carrying molecule.
Q2. How does Creatine Monohydrate work?
A2: When you exercise intensely, your muscles use up ATP for energy. Creatine monohydrate is stored in muscles as phosphocreatine. When ATP breaks down to ADP (adenosine diphosphate), phosphocreatine donates a phosphate group to ADP, converting it back into ATP. This replenishes the energy supply in muscles, allowing them to perform at a high level for longer.
Q3. Does Creatine Monohydrate cause weight gain?
A3: It may cause some weight gain, usually in the form of water weight. As creatine enters muscle cells, it attracts water, leading to increased muscle cell volume. This can result in a few pounds of weight gain in the initial weeks of taking creatine. However, over time, with proper exercise, some of this weight gain may also be due to actual muscle growth.
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