Urolithin A Powder

What is urolith?

Urolithin is a class of polyphenolic compounds, whose precursors mainly come from pomegranates, nuts, and berries. When the human body ingests food containing tannic acid, specific gut microbiota will convert tannic acid into urolithin. Common types include urolithin A, urolithin B, urolithin C, and urolithin D, with urolithin A being the most extensively studied.

1.Dietary supplements: anti-aging, improving muscle function, enhancing cellular energy metabolism.

2.Functional foods: added to protein bars, solid drinks, functional gummies, etc.

3.Sports nutrition: Relieve exercise fatigue, improve muscle endurance and recovery ability.

4.Sleep regulation products: improve circadian rhythm disorders by regulating rhythm genes.

5.Women's Health Products: Delaying Ovarian Aging and Improving Oocyte Quality.

6.Cosmetic materials: anti-aging skin care products, antioxidant essence.

1. Urolithin A can activate autophagy through PINK1/Parkin dependent and PINK1/Parkin independent pathways. Mitophagy is a process of breaking down old or damaged mitochondria and recovering proteins to produce new cells. This ability enables urolithin A to reverse the aging characteristics of hematopoietic stem cells and restore their hematopoietic capacity.

2. Urolithin A can intervene in aging skin fibroblasts and help improve

Type I collagen effectively reduces the expression of matrix metalloproteinase-1 (MMP-1). Urolithin A affects the catalytic activation of cellular tyrosinase through competitive inhibition, thereby reducing skin pigmentation.

3. Urolitin A can inhibit the nuclear factor kappa B and Akt/mitogen activated protein kinase signaling pathways, and further reduce the production of inflammatory mediators by lowering the mRNA and protein levels of cyclooxygenase-2. It can regulate the production of cytokines, reduce the production of pro-inflammatory cytokines, while enhancing the synthesis of anti-inflammatory cytokines such as interleukin-10 (IL-10) and the expression of transforming growth factor.

Q1: What is the difference between urolith A and tannic acid?

Urolithin A is an active product generated by the metabolism of tannic acid by gut microbiota. Direct supplementation of tannic acid relies on the individual's gut microbiota conversion ability, and the conversion efficiency varies greatly among different populations. However, direct supplementation of urolithin A has a more stable and controllable effect.

Q2: Can urolith A be used together with other ingredients?

Yes. Research has shown that urolithin A has a synergistic effect with NAD+precursors such as NMN and NR. It can also be compounded with components such as resveratrol, coenzyme Q10, collagen peptides, melatonin, and applied in different scenarios such as anti-aging, sleep regulation, and exercise nutrition.

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