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Nicotinamide

Nicotinamide

Nicotinamide, also known as niacinamide, is the active amide form of vitamin B3 (a niacin - class vitamin). It belongs to the water - soluble B - group vitamins and is widely used in three major fields: health products, pharmaceuticals and cosmetics. Meanwhile, it serves as a core substance for regulating human energy metabolism and physiological functions.
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Product Details ofNicotinamide

product-780-311Question

What does Nicotinamide do for the body?

Nicotinamide (a form of Vitamin B3) is crucial for cellular energy, DNA repair, and function, acting as a precursor to NAD+, helping with skin health (acne, aging, sun damage), brain function, metabolism, and potentially reducing risk for certain cancers and diabetes.

 

Product-information

Product name:

Nicotinamide

Synonyms:

3-Pyridinecarboxamide; Niacinamide; Vitamin B3

CAS No.:

98-92-0

Specification:

98.5%-101.5%

Storage:

Store at room temperature. Protect from moisture and light.

Shelf life:

24 months from date of production

Origin:

China

Certificate:

ISO9001/FSSC 22000

Process:

3-cyanopyridine → Hydrolysis → Filter pressing → Decoloration → Filter pressing → Crystalizing → Filtration → Drying → Sifting → Packaging → Nicotinamide

Specification

Test Item

Standard

Test Methods

Product name:

Nicotinamide

/

Appearance:

White crystalline powder or granular powder

Visual

Odor & Taste:

Odourless or almost odourless, taste bitter

Smell

Identification A:

Consistent with Reference Standard

IR

Identification B

(Ratio:A245/A262):

0.63-0.67

UV

Assay:

98.5%-101.5%

HPLC

Melting Point:

128℃-131℃

Melting point

apparatus

Loss on drying:

NMT 0.50%

Silica gel drier

Heavy metals:

NMT 0.003%

Colorimetry

Residue on ignition:

NMT 0.1%

High temperature

ignition

Readily

carbonizable substances:

The Sample Solution Has no

more color than Reference solution

Colorimetry

Solubility:

Free Soluble In Water And In ethanol, Slightly Soluble In methylene Chloride And Glycerol

/

 

application

  1. Cosmetics Field:Nicotinamide serves as a core functional ingredient in skincare products, with three key effects: whitening, anti-inflammation and skin repair. It inhibits the transfer of melanin to the epidermis to fade spots and dullness; regulates sebum secretion; and promotes lipid synthesis in the stratum corneum. It is suitable for various skincare formulations such as serums, lotions, creams and facial masks.
  2. Healthcare Product Field:As a water-soluble vitamin supplement, nicotinamide is often formulated into tablets, capsules, stick-pack powders and other dosage forms. It can be used alone or compounded with other B-group vitamins to meet the daily nutritional needs of the human body. Compared with nicotinic acid, it does not cause skin flushing as a side effect, has higher tolerability, is suitable for long-term oral administration, and can also be added to sports nutrition products to support metabolic recovery.
  3. Food Additive Field:Nicotinamide can be used as a nutritional fortifier and added to cereals, dairy products, beverages, infant supplementary foods and meal replacement foods in accordance with national standards, so as to increase the vitamin content of foods and prevent health problems caused by vitamin B3 deficiency in the population.
  4. Feed Field:Nicotinamide can also be used as a feed additive in livestock, poultry and aquaculture to promote animal growth and development and improve feed conversion rate.

 

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  • Dosage Form Compatibility: Nicotinamide boasts excellent water solubility and dispersibility. It can be formulated into water-soluble preparations (e.g., oral liquids, serums, stick-pack powders) and can also be processed into oil-soluble microparticles via microencapsulation technology for incorporation into oil-based formulations such as creams and lotions, overcoming the common challenge of most water-soluble ingredients being difficult to integrate into oil-phase systems.
  • High Safety: Compared with nicotinic acid, nicotinamide does not induce skin flushing as a side effect when administered orally, making it suitable for long-term use as a nutritional supplement. When applied topically at a concentration of 2%–5%, it is non-irritating to most skin types with a low incidence of adverse reactions, and thus can be widely incorporated into daily skincare products and pharmaceutical preparations.
  • High purity: The assay of Nicotinamide reaches 99%. The concentration of active substances is sufficient, which better ensures the efficacy stability of end products (such as pharmaceutical preparations and health products).

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Q1: What does Nicotinamide do to the face?

A1: Niacinamide (Vitamin B3) benefits your face by strengthening the skin barrier, boosting hydration, reducing redness/inflammation (good for acne/rosacea), minimizing pores, controlling oil, brightening dark spots/hyperpigmentation, and smoothing fine lines/wrinkles, all while protecting against UV damage and improving overall texture for clearer, healthier, radiant skin.

 

Q2: Does Nicotinamide help you sleep?
A2: Yes, niacinamide (a form of Vitamin B3) can support restful sleep by helping produce calming neurotransmitters like serotonin, which regulates mood and sleep, and it may help regulate the sleep-wake cycle, potentially improving sleep efficiency.

 

Q3: Is nicotinamide the same as vitamin B3?
A3: Vitamin B3 is the umbrella term, and niacinamide (nicotinamide) is one form of it, alongside niacin (nicotinic acid).

 

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