Tolerance To Bile Salts

   Studies have shown that bile salts can destroy cell membranes and reduce the survival rate of probiotics. The survival of probiotics after reaching the intestine depends largely on their tolerance to bile salts. In addition, the concentration of bile salt and the characteristics of the strain itself determine the inhibitory effect of bile salt on the strain. Only the strain that can grow and metabolize at the normal physiological bile salt concentration may survive the intestinal digestion process. Lactobacillus helveticus still has a survival rate of 106 CFU/mL at a bile salt concentration of 5 g/L, indicating that it has a good tolerance to bile salts.