The effect of Lactobacillus reuteri on murine enteritis

   The effect of Lactobacillus reuteri on murine enteritis: At present, chemical agents are commonly used to induce enteritis in experimental mice. The commonly used chemical agents are acetic acid or methotrexate. To establish an experimental animal model of ulcerative colitis induced by acetic acid in rats. They found that feeding rats intestinal-specific Lactobacillus reuteri at a dose of 5×107 to 7×107 cfu immediately after acetic acid feeding can prevent the development of ulcerative colitis inflammation. Methotrexate (MTX) is an anti-tumor chemical drug used in humans, and it can also be used as a drug to treat rheumatoid diseases. However, the drug can cause cytotoxin damage to the intestinal mucosa and destroy the gastrointestinal microecological level.